Carrie Preston as Arlene Fowler (Seasons 1-5)
Deborah Ann Woll as Jessica Hamby (Seasons 1-5)
While alive, Jessica was a recluse who lived under her parents' thumb, but after Bill was forced to turn her into a vampire by the vampire tribunal, she became a wild child, seeking to explore her newfound freedom and power -- much to the chagrin of her new caretaker, Bill. She soon finds solace in the arms of Hoyt Fortenberry.
Jim Parrack as Hoyt Fortenberry (Seasons 1-5)
A friend of Jason, Hoyt is in many ways his polar opposite: a nice guy looking for that special gal to settle down with. He thinks he finds "the one" in Jessica, but her vampirism throws a wrench in the plans -- especially when it comes to the approval of his domineering mother.
Todd Lowe as Terry Bellefleur (Seasons 1-5)
Kristin Bauer as Pam (Seasons 1-5)
Pam is a stylish and sassy "omnisexual" offspring of Eric who is his primary aide in running Fangtasia, contributing a wry, sarcastic sense of humor to the proceedings.
Mariana Klaveno as Lorena (Seasons 1-3)
Lorena gave Bill the "gift" of eternal life soon after the Civil War, forcing him to leave his wife and kids forever. She and Bill remained a couple into the early 20th century, feeding on humans with sadistic glee until he became weary of their lifestyle and left Lorena. However, being his maker, she still has some pull over him and is none too pleased to see him dating a "human" like Sookie.
Mehcad Brooks as "Eggs" Benedict Talley (Seasons 1-2)
Jessica Tuck as Nan Flanagan (Seasons 1-4)
Spokesperson for the American Vampire League, Nan seeks to gain the trust of the human population, but is her agenda really just about forming one big happy family between humans and vampires?
Denis O'Hare as Russell Edgington (Seasons 3 and 5)
Russell is the flamboyant 3,000-year-old vampire king of Mississippi, a Southern gentleman with a dark side. When his long-time boyfriend Talbot strays, Russell's jealous streak flares, burning those in his path.